RBC Genotyping Testing for RHCE and Extended Blood Groups

Test description

This is a PCR-based assay for the identification of multiple alleles encoding human erythrocyte antigens in genomic DNA. The IDCORE XTTM test identifies 29 genomic variants responsible for normal and altered expressions of human red cell antigens in the Rh, Kell, Kidd, Duffy, MNS, Diego, Dombrock, Colton, Cartwright, and Lutheran blood group systems. These tests are alternatives to serological testing in cases of discordant antigen phenotyping results, autoimmune hemolytic anemia, chronically transfused patients with previously identified antibodies, patients receiving treatment with anti-CD38, and patients with transfusion dependent diseases such as sickle cell disease and thalassemia.

Note: This test is not recommended for patients with a history of bone marrow (stem cell) transplant.

RBC Genotyping Testing for RHCE and Extended Blood Groups (PDF) 

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Specimen and requisition requirements

Specimen(s):
Two (2) full 5-7 ml EDTA (lavender) tube mixed thoroughly by gentle agitation. Within 14 days of collection.

Label specimen with the required minimum information: patient’s last name, first name, PHIN or hospital number or other unique identifier, date of collection, facility name, and phlebotomist initials.

Complete Requisition (must include):

  • Patient's last name, first name, date of birth and PHIN or hospital number or other unique identifier
  • Facility Name
  • Date of collection
  • Name, facility, address, contact number of individual to whom the report will be sent

Requisition

Requisition for Blood Group Genotyping - Patient (NIRL) (PDF) 
(Electronic Fillable Form)

Demande de génotypage sanguin (patient) (PDF) 
(Peut être rempli en ligne)

Pre-shipping storage

Recommended Refrigeration 1-10°C.

Shipping instructions

Submit samples as soon as possible after collection.

Shipping

Ship in a container that will maintain temperature at 4oC to 25oC.
Select shipping method for container to arrive at testing site within 48 hours.

Note: Protect from freezing.

Send to

Canadian Blood Services
Winnipeg Centre
Diagnostic  Services Crossmatch Laboratory
777 William Ave.
Winnipeg, MB R3E 3R4
Tel: 204-789-1085
Fax: 204-779-8593